Study Instructions

NAD+ Complete Week Instructions

The intervention week: 7 consecutive nights of nighttime NAD+ Complete while your Oura Ring keeps tracking your sleep.

Purpose

This week assesses the impact of nighttime NAD+ Complete on your deep sleep. We compare your sleep during this week against your baseline week - looking at deep sleep duration plus total sleep time, sleep efficiency, REM sleep, resting heart rate, and heart rate variability, all measured by your Oura Ring.

The Protocol

Take 2 capsules of NAD+ Complete, 30-60 minutes before bedtime, each night for 7 consecutive nights. Continue to wear your Oura Ring nightly. Apart from the supplement, keep your routine the same as it was during your baseline week.

Your Group

How you handle any morning NAD+ precursors depends on the group you selected in the NAD+ Complete Start Survey:

The "Add" Protocol (Group 1) You were not taking NAD+ precursors during baseline. Add NAD+ Complete 30-60 minutes before bedtime. Keep everything else the same.

The "Replace" Protocol (Group 2) Stop your morning precursors and take NAD+ Complete at night, 30-60 minutes before bed (640 mg total daily dose).

The "Combined" Protocol (Group 3) Continue your morning precursors and add NAD+ Complete at night (up to 1,250 mg total daily dose). If your morning dose exceeds 610 mg, reduce it to 610 mg for the duration of the intervention week.

What to Do & What Not to Do

What to Do

Take 2 capsules of NAD+ Complete 30-60 minutes before bedtime
Take it every night for 7 consecutive nights
Wear your Oura Ring to bed every night
Keep the rest of your routine exactly as it was during baseline
Complete optional daily notes each morning

What Not to Do

Skip nights - the protocol requires 7 consecutive nights
Start any other new supplements this week
Take melatonin or other sleep aids
Dramatically change your sleep schedule
Take morning NAD+ precursors outside your group protocol

Side effects NAD+ Complete may cause mild, typically transient effects such as mild gastrointestinal discomfort, mild headache, changes in sleep onset, or vivid dreams. If you experience side effects or health concerns, stop taking the study product and contact the research team at research@renuebyscience.com (or use Report Adverse Event on your dashboard). If symptoms are severe or urgent, seek medical care immediately.

Day-by-Day Checklist

Use this checklist to stay on track each night of the NAD+ Complete week.

Day 1 First night: take 2 capsules of NAD+ Complete 30-60 minutes before bed. Wear your Oura Ring.
Day 2 NAD+ Complete 30-60 minutes before bed. Wear your Oura Ring. Optional daily notes by 10 AM.
Day 3 NAD+ Complete 30-60 minutes before bed. Wear your Oura Ring. Optional daily notes by 10 AM.
Day 4 NAD+ Complete 30-60 minutes before bed. Wear your Oura Ring. Halfway through the week!
Day 5 NAD+ Complete 30-60 minutes before bed. Wear your Oura Ring. Optional daily notes by 10 AM.
Day 6 NAD+ Complete 30-60 minutes before bed. Wear your Oura Ring. Optional daily notes by 10 AM.
Day 7 Final night of the protocol. NAD+ Complete 30-60 minutes before bed. Wear your Oura Ring.

What happens next? After your 7th night, the NAD+ Complete End Survey unlocks on your dashboard. Submitting it completes your participation - your reward code is emailed to you, and we will notify you when your personalized results are ready to view.